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[SHOW NOTES] Animal Models in Neuroscience Research

In this episode, we discussed commonly used animal models in neuroscience research. Beyond that, we also discussed some less commonly used model organisms and how their unique attributes can help answer specific scientific questions.

Listen to the episode here

Find a great review about the most commonly used animal models in research here

We also discussed some more unique animal models, and how we can gain useful knowledge from understanding a variety of species, not necessarily mammalian animals. This ties in with the ethical guidelines that guide animal-based research in the UK:

NC3Rs (replacement, reduction, refinement) is a UK-based scientific organisation dedicated to helping the research community worldwide to identify, develop and use 3Rs technologies and approaches.

It also raises issues with anthropocentricism in research. Here is an interesting opinion piece (Bridges & Chittka, 2023):

We covered quite a few examples of insightful studies on less common model organisms:

Bees as a model for social learning

Bee colonies (the superorganism) as a model for decision-making

Ants as a model for epigenetic remodelling of brain function, social behaviour, and ageing

Songbirds as a model for vocal learning

Non-mammalian (yeast) models for understanding the neurobiology of epilepsy


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