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Is Coffee Good or Bad?

In this episode, we discussed the controversial scientific evidence for the potential benefits and harmful effects of caffeine.


How did caffeine shape human behaviour and influence human history?


How Caffeine Addiction Changed History (ft. Michael Pollan) | WIRED


How does caffeine influence cognition and health?


Review of caffeine’s effects on cognitive, physical, and occupational performance (McLellan et al., 2016) https://www.sciencedirect.com/science/article/pii/S0149763416300690


Coffee, Caffeine, and Health


What are the neurobiological effects of caffeine?

“The role of adenosine receptors in the central action of caffeine

John W. Daly, Dan Shi, Olga Nikodijevic,* and Kenneth A. Jacobson”


Effects of Long-Term Caffeine Consumption on the Adenosine A1 Receptor in the Rat Brain: an In Vivo PET Study with [18F]CPFPX


“Using caffeine and other adenosine receptor antagonists and agonists as therapeutic tools against neurodegenerative diseases” MarlaRivera-OliverManuelDíaz-Ríos


How can caffeine shape the brain?


Coffee enhances brain functional connectivity (Kim et al., 2021) https://www.nature.com/articles/s41598-021-93849-7


Habitual coffee drinkers have distinct brain connectivity (Mahalhaes et al., 2021) https://www.nature.com/articles/s41380-021-01075-4


Caffeine increases brain entropy (Chang et al., 2018) https://www.nature.com/articles/s41598-018-21008-6#ref-CR9




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